Everyone Loses Their Minds (Joker Mind Loss)
From a dramatic scene in the 2008 feature film "The Dark Knight", in which the Joker talks about the different reactions the public has to similar situations; in this case, the difference between threatening the public and threatening the mayor.
The meme is for a disparity comparison, with the one case at the top, and the bottom case ending in '.. and everyone loses their minds!"
TOP: Screw up your grammar in real life and no one cares"
BOTTOM: Mess up your grammar on Reddit and everyone loses their minds!"